Recent publications

 

Designing and implementing a COPD discharge care bundle.

Thorax

 

Downregulation of the serum response factor/miR-1 axis in the quadriceps of patients with COPDThorax

 

The COPD assessment test (CAT): response to pulmonary rehabilitation. A multicentre, prospective study.Thorax.

 

Continuous transcutaneous submental electrical stimulation in obstructive sleep apnea: a feasibility study.Chest.

 

Nocturnal asthma monitoring by chest wall electromyography

Thorax.

 

Neural respiratory drive as a physiological biomarker to monitor change during acute exacerbations of COPD.

Thorax.

 

Yin Yang 1 expression and localisation in quadriceps muscle in COPD Arch Bronch

 

Atelectasis and Survival after Bronchoscopic Lung Volume Reduction for COPD. ERJ

 

Quadriceps Myostatin Expression in COPD ERJ

 

Outpatient pulmonary rehabilitation following acute exacerbations of COPD. Thorax

 

COPD in England: a comparison of expected, model-based prevalence and observed prevalence from general practice data. J Public Health

 

Sleep-disordered breathing in neuromuscular disease with diaphragm paralysis questionnaire. ERJ

 

Acute ischaemic hemispheric stroke is associated with impairment of reflex in addition to voluntary cough ERJ

 

Sniff nasal inspiratory pressure versus IC/TLC ratio as predictors of mortality in COPD

Respir Med

 

The prevalence of Quadriceps Weakness in COPD    and the Relationship with Disease Severity ERJ

 

Assessment of respiratory muscle strength in motor neurone disease: is asking enough? ERJ

 

Increased load on the respiratory muscles in obstructive sleep apnea Resp Physiol Neurobiol

 

Unilateral extrapulmonary airway bypass in advanced emphysema Ann Thorac Surg

 

Does physical inactivity cause COPD? Clin Sci

 

Abdominal muscle fatigue following exercise in COPD Resp Res

 

Ultrasound measurement of quadriceps cross sectional area  Thorax

 

Neural respiratory drive in obesity Thorax

 

Physiological properties of the human diaphragm muscle and the effect of COPD J Physiol

 

Neural Respiratory Drive in Healthy Subjects and in COPD ERJ

 

Quadriceps strength in scoliosis ERJ

 

Sleep-disordered breathing in unilateral diaphragm paralysis or severe weakness. ERJ

 

Vitamin D receptor genotypes influence quadriceps strength in chronic obstructive pulmonary disease. Am J Clin Nutr

 

Neural respiratory drive during apnoeic events in obstructive sleep apnoea.

Eur Resp J

 

A novel technique for non-volitional assessment of quadriceps muscle endurance in humans.

J App Physiol

 

The value of multiple tests of respiratory muscle strength Thorax

 

Quadriceps strength predicts mortality in patients with moderate to severe chronic obstructive pulmonary disease.      Thorax

 

A prospective study of decline in fat free mass and skeletal muscle strength in chronic obstructive pulmonary disease. Resp Res

 

 

Lab meeting at The Royal Brompton Hospital.

(L-R Back row) Dr Zudin Puthucheary, Dr Joerg Steier, Dr Patrick Murphy, Charles Reilly, Dr Nicholas Hopkinson, Dr William Man, Professor Mike Polkey, Professor John Moxham, (L-R Front) Dr Abigail Jackson, Dr Amanda Sathyapala, Dr Laura Mendoza, Dr John Seymour, Dr Sam Kemp.

 

London Respiratory Muscle Group

The London Respiratory Muscle Group

The London Respiratory Muscle Group is a collaboration between scientists and clinicians working in the field of respiratory physiology and skeletal muscle function in health and disease. It has been producing research for more than 25 years and has weekly meetings rotating through the main research centres.

 

Current areas of interest include skeletal muscle dysfunction in COPD, physical activity monitoring, sleep disordered breathing and neural drive, home mechanical ventilation and novel bronchoscopic lung volume reduction techniques for emphysema.

 

The group are part of the PROactive collaboration an EU project developing a patient reported outcome for Physical Activity in COPD.

 

Research in our group has been sponsored by grants from sources including The MRC, The Wellcome Trust, The British Lung Foundation, the NIHR and The Moulton Charitable Foundation.

 

Universities

Imperial College

Guy’s, King’s St Thomas’ School of Medicine and Dentistry

 

Hospitals

King’s College Hospital

 

Royal Brompton Hospital

 

St Thomas’ Hospital

 

Harefield Hospital

 

Chelsea and Westminster Hospital

 

To contact us:

Phone:  020 73497775

Fax:      020 73497778

E-mail: info@respiratorymuscle.com

 

 

 

Lab meetings

 

2012

Jan                     KCH

Feb                     STH

Mar                     RBH

Apr                     KCH

May                    STH

Jun                     RBH

Jul                      KCH

Aug                    STH

Sep                    RBH