London Respiratory Muscle Group

Publications 2005-8

Stubbings, AK, AJ Moore, M Dusmet, P Goldstraw, TG West, MI Polkey, and MA Ferenczi. 2008, "Physiological Properties of Human Diaphragm Muscle Fibres and the Effect of Chronic Obstructive Pulmonary Disease." J Physiol 586:2637-50 http://www.ncbi.nlm.nih.gov/

 

Steier, J, CJ Jolley, J Seymour, S Kaul, YM Luo, GF Rafferty, N Hart, MI Polkey, and J Moxham. 2008, "Sleep-Disordered Breathing in Unilateral Diaphragm Paralysis or Severe Weakness." Eur Respir J 32:1479-87 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=18684853.

 

Romer, LM, and MI Polkey. 2008, "Exercise-Induced Respiratory Muscle Fatigue: Implications for Performance." J Appl Physiol 104:879-88 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=18096752.

 

Nickol, AH, N Hart, NS Hopkinson, CH Hamnegard, J Moxham, A Simonds, and MI Polkey. 2008, "Mechanisms of Improvement of Respiratory Failure in Patients with Copd Treated with Niv." Int J Chron Obstruct Pulmon Dis 3:453-62 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=18990974.

 

Luo, YM, HD Wu, J Tang, C Jolley, J Steier, J Moxham, NS Zhong, and MI Polkey. 2008, "Neural Respiratory Drive During Apnoeic Events in Obstructive Sleep Apnoea." Eur Respir J 31:650-7 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=18032443.

 

Luo, YM, J Moxham, and MI Polkey. 2008, "Diaphragm Electromyography Using an Oesophageal Catheter: Current Concepts." Clin Sci (Lond) 115:233-44 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=18782085.

 

Hopkinson, NS, KW Li, A Kehoe, SE Humphries, M Roughton, J Moxham, H Montgomery, and MI Polkey. 2008, "Vitamin D Receptor Genotypes Influence Quadriceps Strength in Chronic Obstructive Pulmonary Disease." Am J Clin Nutr 87:385-90 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=18258629.

 

Harraf, F, K Ward, W Man, G Rafferty, K Mills, M Polkey, J Moxham, and L Kalra. 2008, "Transcranial Magnetic Stimulation Study of Expiratory Muscle Weakness in Acute Ischemic Stroke." Neurology 71:2000-7 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=19064882.

 

Harikumar, G, J Moxham, A Greenough, and GF Rafferty. 2008, "Measurement of Maximal Inspiratory Pressure in Ventilated Children." Pediatr Pulmonol 43:1085-91 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=18846557.

 

Chatwin, M, AH Nickol, MJ Morrell, MI Polkey, and AK Simonds. 2008, "Randomised Trial of Inpatient Versus Outpatient Initiation of Home Mechanical Ventilation in Patients with Nocturnal Hypoventilation." Respir Med 102:1528-35 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=18774702.

 

Cairns, H, B Hendry, A Leather, and J Moxham. 2008, "Outcomes of the European Working Time Directive." BMJ 337:a942 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=18669572.

 

Bonnici, KS, WD Man, and MI Polkey. 2008, "Acute Respiratory Distress in a Patient Using Non-Invasive Ventilation." Thorax 63:802, 44 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=18728204.

 

Barreiro, E, AM Schols, MI Polkey, JB Galdiz, HR Gosker, EB Swallow, C Coronell, and J Gea. 2008, "Cytokine Profile in Quadriceps Muscles of Patients with Severe Copd." Thorax 63:100-7 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=17875568

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Alty, SR, WD Man, J Moxham, and KC Lee. 2008, "Denoising of Diaphragmatic Electromyogram Signals for Respiratory Control and Diagnostic Purposes." Conf Proc IEEE Eng Med Biol Soc 2008:5560-3 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=19163977.

 

Toma, TP, OM Kon, W Oldfield, R Sanefuji, M Griffiths, F Wells, S Sivasothy, M Dusmet, DM Geddes, and MI Polkey. 2007, "Reduction of Persistent Air Leak with Endoscopic Valve Implants." Thorax 62:830-33 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=17726171.

 

Swallow, EB, D Reyes, NS Hopkinson, WD Man, R Porcher, EJ Cetti, AJ Moore, J Moxham, and MI Polkey. 2007, "Quadriceps Strength Predicts Mortality in Patients with Moderate to Severe Chronic Obstructive Pulmonary Disease." Thorax 62:115-20 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=17090575.

 

Swallow, EB, HR Gosker, KA Ward, AJ Moore, MJ Dayer, NS Hopkinson, AM Schols, J Moxham, and MI Polkey. 2007, "A Novel Technique for Nonvolitional Assessment of Quadriceps Muscle Endurance in Humans." J Appl Physiol 103:739-46 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=17569771.

 

Steier, J, S Kaul, J Seymour, C Jolley, G Rafferty, W Man, YM Luo, M Roughton, MI Polkey, and J Moxham. 2007, "The Value of Multiple Tests of Respiratory Muscle Strength." Thorax 62:975-80 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=17557772.

 

Sathyapala, SA, P Kemp, and MI Polkey. 2007, "Decreased Muscle Ppar Concentrations: A Mechanism Underlying Skeletal Muscle Abnormalities in Copd?" Eur Respir J 30:191-3 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=17666554.

 

Hopkinson, NS, RC Tennant, MJ Dayer, EB Swallow, TT Hansel, J Moxham, and MI Polkey. 2007, "A Prospective Study of Decline in Fat Free Mass and Skeletal Muscle Strength in Chronic Obstructive Pulmonary Disease." Respir Res 8:25 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=17355636.

 

Dayer, MJ, S Jonville, M Chatwin, EB Swallow, R Porcher, T Sharshar, ET Ross, NS Hopkinson, J Moxham, and MI Polkey. 2007, "Exercise-Induced Depression of the Diaphragm Motor Evoked Potential Is Not Affected by Non-Invasive Ventilation." Respir Physiol Neurobiol 155:243-54 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=16914394.

 

Whyte, GP, M Harries, J Dickinson, and MI Polkey. 2006, "Breathless in the Bath." Br J Sports Med 40:554-5 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=16720891.

 

Swallow, EB, MJ Dayer, WL Oldfield, J Moxham, and MI Polkey. 2006, "Right Hemi-Diaphragm Paralysis Following Cardiac Radiofrequency Ablation." Respir Med 100:1657-9 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=16488125.

 

Schonhofer, B, MI Polkey, S Suchi, and D Kohler. 2006, "Effect of Home Mechanical Ventilation on Inspiratory Muscle Strength in Copd." Chest 130:1834-8 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=17167005.

 

Polkey, MI, and J Moxham. 2006, "Attacking the Disease Spiral in Chronic Obstructive Pulmonary Disease." Clin Med 6:190-6 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=16688981.

 

Nicot, F, N Hart, V Forin, M Boule, A Clement, MI Polkey, F Lofaso, and B Fauroux. 2006, "Respiratory Muscle Testing: A Valuable Tool for Children with Neuromuscular Disorders." Am J Respir Crit Care Med 174:67-74 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=16574932.

 

Mustfa, N, E Walsh, V Bryant, RA Lyall, J Addington-Hall, LH Goldstein, N Donaldson, MI Polkey, J Moxham, and PN Leigh. 2006, "The Effect of Noninvasive Ventilation on Als Patients and Their Caregivers." Neurology 66:1211-7 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=16636239.

 

Moore, AJ, A Stubbings, EB Swallow, M Dusmet, P Goldstraw, R Porcher, J Moxham, MI Polkey, and MA Ferenczi. 2006, "Passive Properties of the Diaphragm in Copd." J Appl Physiol 101:1400-5 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=16840573.

 

Lasserson, D, K Mills, R Arunachalam, M Polkey, J Moxham, and L Kalra. 2006, "Differences in Motor Activation of Voluntary and Reflex Cough in Humans." Thorax 61:699-705 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=16601089.

 

Hopkinson, NS, KI Eleftheriou, J Payne, AH Nickol, E Hawe, J Moxham, H Montgomery, and MI Polkey. 2006, "+9/+9 Homozygosity of the Bradykinin Receptor Gene Polymorphism Is Associated with Reduced Fat-Free Mass in Chronic Obstructive Pulmonary Disease." Am J Clin Nutr 83:912-7 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=16600946.

 

Hamnegard, CH, MI Polkey, A Thylen, F Nilsson, H Schersten, and B Bake. 2006, "Effect of Lung Volume Reduction Surgery for Emphysema on Diaphragm Function." Respir Physiol Neurobiol 150:182-90 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=16009600.

 

Glerant, JC, N Mustfa, WD Man, YM Luo, G Rafferty, MI Polkey, and J Moxham. 2006, "Diaphragm Electromyograms Recorded from Multiple Surface Electrodes Following Magnetic Stimulation." Eur Respir J 27:334-42 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=16452589.

 

Dayer, MJ, NS Hopkinson, ET Ross, S Jonville, T Sharshar, M Kearney, J Moxham, and MI Polkey. 2006, "Does Symptom-Limited Cycle Exercise Cause Low Frequency Diaphragm Fatigue in Patients with Heart Failure?" Eur J Heart Fail 8:68-73 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=16081318.

 

Sharshar, T, NS Hopkinson, ET Ross, S Jonville, MJ Dayer, AH Nickol, F Lofaso, J Moxham, and MI Polkey. 2005, "Motor Control of the Costal and Crural Diaphragm--Insights from Transcranial Magnetic Stimulation in Man." Respir Physiol Neurobiol 146:5-19 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=15733775.

 

Rafferty, GF, N Mustfa, WD Man, K Sylvester, A Fisher, M Plaza, M Davenport, S Blaney, J Moxham, and A Greenough. 2005, "Twitch Airway Pressure Elicited by Magnetic Phrenic Nerve Stimulation in Anesthetized Healthy Children." Pediatr Pulmonol 40:141-7 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=15965896.

 

Nickol, AH, N Hart, NS Hopkinson, J Moxham, A Simonds, and MI Polkey. 2005, "Mechanisms of Improvement of Respiratory Failure in Patients with Restrictive Thoracic Disease Treated with Non-Invasive Ventilation." Thorax 60:754-60 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=15939731.

 

Moore, AJ, J Moxham, and MI Polkey. 2005, "Diaphragm Weakness as a Cause of Breathlessness after Anatomically Distant Surgery." Thorax 60:786-7 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=16135683.

 

McMullin, MF, D Bareford, P Campbell, AR Green, C Harrison, B Hunt, D Oscier, MI Polkey, JT Reilly, E Rosenthal, K Ryan, TC Pearson, and B Wilkins. 2005, "Guidelines for the Diagnosis, Investigation and Management of Polycythaemia/Erythrocytosis." Br J Haematol 130:174-95 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=16029446.

 

Man, WD, NS Hopkinson, F Harraf, D Nikoletou, MI Polkey, and J Moxham. 2005, "Abdominal Muscle and Quadriceps Strength in Chronic Obstructive Pulmonary Disease." Thorax 60:718-22 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=15923239.

 

Luo, YM, and J Moxham. 2005, "Measurement of Neural Respiratory Drive in Patients with Copd." Respir Physiol Neurobiol 146:165-74 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=15766905.

 

Hopkinson, NS, TP Toma, DM Hansell, P Goldstraw, J Moxham, DM Geddes, and MI Polkey. 2005, "Effect of Bronchoscopic Lung Volume Reduction on Dynamic Hyperinflation and Exercise in Emphysema." Am J Respir Crit Care Med 171:453-60 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=15579725.

 

Hart, N, I Laffont, AP de la Sota, M Lejaille, G Macadou, MI Polkey, P Denys, and F Lofaso. 2005, "Respiratory Effects of Combined Truncal and Abdominal Support in Patients with Spinal Cord Injury." Arch Phys Med Rehabil 86:1447-51 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=16003679.

 

Chetta, A, AK Rehman, J Moxham, DH Carr, and MI Polkey. 2005, "Chest Radiography Cannot Predict Diaphragm Function." Respir Med 99:39-44 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=15672847.